The production of polymer nanocomposites with natural clays as reinforcement has been thoroughly researched for many researchers. The authors always have been seeking for better properties compared to the neat polymer without reinforcement. That is, the great appeal of these types of materials. The most commonly used natural clays as reinforcement in polymer nanocompostes are montmorillonite (MMT), halloysite, and kaolinite. Thus, the organic modification of these clays has also been studied to improve the clay interlayer space (intercalation), due to the creation of an affinity with the polymer matrix and reach better properties than neat polymer. In this context, this review article first discusses an approach regarding the intercalation techniques of kaolinite clay using different intercalate molecules. Then, it discusses the polymer nanocomposite processing such as polymers in solution, melt blending, and in situ polymerization using kaolinite as reinforcement.