A Molecular Docking Study of Lopinavir towards SARS-COV-2 Target Protein
Abstract
COVID-19 was the trigger for the pandemic triggered by SARS-CoV-2. Potential treatments are being used to treat it but there is no specific drug for it. In order to get a particular drug, several drug design techniques are used in which molecular docking plays a critical role in computer-assisted drug design. In this study, we tested the Lopinavir (LV) molecular docking of the SARS-CoV-2 receptor binding spike proteins. We developed ADMET properties consistent with the expected ADMET parameters provided by Lipinski's rule using Datawarrior software version 5.2.1.