Friction stir processing (FSP) has been used to prepare composite materials by admixing copper and aluminum powder blends with Cu/Al mass ratios 2:1, 1:1 and 1:2 into Ti6Al4V alloy matrix using a nickel superaloy FSP tool. Structural evolution of a stir zone material was studied as depended on the Cu/Al mass ratio and number of FSP passes. The content of α(α’)-Ti increased in all samples after the first FSP pass but then slowly reduced with the FSP pass number increased to 4. The inverse dependence of β-Ti content on the FSP pass number was demonstrated. Intermetallic compounds TixCuyAlz, TixAly and TixСuy were detected in the stir zone obtained by admixing 2:1, 1:1 and 1:2 powder blends. The maximum tensile strength in the range 1050-1200 MPa was achieved after 4-pass FSP on all samples with ~35% reduction of the ductility as compared to that of the as-received alloy. The stir zones also had increased microhardness numbers as measured across the stir zone section perpendicular to the FSP tool travel direction.