Hematopoietic Potentials of Musa paradisiaca Stem Sap
Abstract
Hematopoiesis is the process by which blood cells, including red and white blood cells, are produced in the bone marrow. Musa paradisiaca, through its astringent properties, may help stop bleeding by promoting vasoconstriction and clot formation when applied to wounds. This study assessed the hematopoietic potentials of the stem sap of Musa paradisica (SSMP). The SSMP was obtained from disruptive methods. Wistar Rats are fed with 5mls of SSMP twice daily i.e morning and evening for 28 days. At the end of the experimental period, the rats were anaesthetized using chloroform and the blood was collected through cardiac puncture. The blood was collected into EDTA bottles and analyzed for full blood count and differentials using automated hematology analyzer. The results were in the range of 9.75 - 16.80 x103/µL for white blood cell, WBC, 8.21 - 9.12x106/µL for red blood cell, RBC, 12.70 – 14.13 g/dL for haemoglobin, HGB, 54.83 -57.45 fL for Mean corpuscular volume, MCV, 45.50 - 51.65% for hematocrit, HCT, 13.15 - 15.70 pg for Mean corpuscular haemoglobin, MCH, 23.65 - 28.10 g/dL for mean corpuscular haemoglobin concentration, MCHC, 690.00-1007.50 x 103/µL for platelets, 66.85 – 74.58% for lymphocytes, 7.45 – 12.68% for neutrophils and 17.25 - 23.53% for mixed cell count including basophils, monocytes, and eosinophils. Analysis of variance showed that there were no significant differences (p>0.05) across the various treatments. A positive correlation between WBC counts and HGB levels suggests a physiological relationship, potentially indicating an inflammatory response. Similarly, significant positive relationships between RBC count and HGB, as well as RBC count and HCT, are crucial for understanding blood health. In conclusion, results showed no significant differences across treatments, but correlations between blood parameters suggested potential physiological relationships. The absence of significant changes hints at physiological resistance, requiring further research into specific mechanisms and long-term effects.